2024 Proheart dosing

ProHeart 6 is indicated for use in dogs six months of age and older for the prevention of heartworm disease caused by Dirofilaria immitis for 6 months. ProHeart 6 is indicated for the treatment of existing larval and adult hookworm (Ancylostoma caninum and Uncinaria stenocephala) infections. ProHeart 6 (moxidectin) Dosage And AdministrationMissing a dose of either ProHeart or Simparica Trio can momentarily weaken the protective barrier against parasites. In the event of a missed dose of Simparica Trio, the immediate administration of the medication as soon as it’s remembered, followed by the resumption of the monthly schedule, is advised to maintain its efficacy against …ProHeart 6 administered at 3 times the recommended dose did not adversely affect the reproductive performance of male or female dogs. ProHeart 6 administered up to 5 times the recommended dose in 7-8 month old puppies did not cause any systemic adverse effects.ProHeart 6 administered up to 5 times the recommended dose in 7-8 month old puppies did not cause any systemic adverse effects. In well controlled clinical field studies, ProHeart 6 was used in conjunction with a variety of veterinary products including anthelmintics, antiparasitics, antibiotics, analgesics, steroids, non-steroidal anti …An injectable moxidectin microsphere formulation (ProHeart 12; Zoetis, zoetisus.com) was shown to be 100% effective in the prevention of development of D immitis in dogs that …People should avoid inhalation, contact with eyes, or accidental self-injection. Certification is required before veterinarians and staff administer these products. See Prescribing Information for ProHeart 6 and ProHeart 12. To keep your dog protected from heartworm disease, it’s important to make sure there are no gaps in their protection.dose based on the dog’s weight at the time of treatment. Do not overdose growing puppies in anticipation of their expected adult weight. The following dosage chart may be used as a guide. Some dogs treated with ProHeart 6 in laboratory effectiveness studies developed transient, localized inflammatory injection DOSAGE CHART site reactions.The second ProHeart 12 dose and the additional eight Heartgard Plus doses provided heartworm prevention during this period. Of the 236 dogs that received two annual doses of ProHeart 12, no animals tested positive for the presence of heartworm antigen or circulating MF at any time during this study, indicating complete heartworm prevention for ...heartworm preventive product, ProHeart 6 should be given within one month of the last dose of the former medication. ProHeart 6 eliminates the larval and adult stages of A. caninum and U. stenocephala present at the time of treatment. However, persistent andA single dose of ProHeart 12 was 100% effective in preventing the development of adult JYD-34 heartworms when treatment was initiated 30 days after …Sep 6, 2019 · Background The safety of ProHeart® 12 (PH 12; extended-release injectable suspension; 10% moxidectin in glyceryl tristearate microspheres) was evaluated in four studies using Beagle dogs and one study using ivermectin-sensitive Collies. The recommended dose is 0.5 mg/kg subcutaneously once yearly. Methods Study 1: safety margin was evaluated as 3 treatments of PH 12 (0× (control); 1× ... ProHeart 12-related findings included edema and thickening of the injection site. Ivermectin-Sensitive Collie Safety: In a laboratory study, 15 ivermectin-sensitive Collie dogs in three treatment groups were administered one dose of saline and one dose of ProHeart 12, 21 days apart. Each dog served as its own control and the order of ...ProHeart 6 and ProHeart 12 See Prescribing Information for ProHeart 6 and ProHeart 12. Use ProHeart 6 in dogs 6 months of age or older and ProHeart 12 in dogs 12 months of age or older. Do not administer to dogs that are sick, debilitated, underweight, have a history of weight loss, or to those previously found to be hypersensitive to the drug.People should avoid inhalation, contact with eyes, or accidental self-injection. Certification is required before veterinarians and staff administer these products. See Prescribing Information for ProHeart 6 and ProHeart 12. To keep your dog protected from heartworm disease, it’s important to make sure there are no gaps in their protection.In people that are not tolerant of opioids, a single dose of 40 milligrams or a total daily dose of 80 milligrams of oxycodone has the potential to cause fatal respiratory depressi...Background In a previous study, it was demonstrated that ProHeart® 6 (PH6) (moxidectin, Zoetis) provided only about 20% efficacy in a small six-dog study against a macrocyclic lactone –resistant Dirofilaria immitis isolate (Jd2009–2) when dogs were inoculated with infective third-stage larvae (L3) at the end of the dosing period (ie, 180 …ProHeart 12 prevents the development of heartworm disease caused by D. immitis for 12 months. For dogs not previously on heartworm preventive or having lapsed beyond 12 months of a prior ProHeart 12 dose, the product should be given within 1 month of12 chances to miss a dose! When life gets busy, it can be tough to stay on top of monthly dosing— • and many pet owners do forget.2 Dogs may vomit or spit out the chews, which means you may have to redose. Some dogs refuse to eat "treat-like Is ProHeartProHeart 12 prevents the development of heartworm disease caused by D. immitis for 12 months. For dogs not previously on heartworm preventive or having lapsed beyond 12 months of a prior ProHeart 12 dose, the product should be given within 1 month of exposure to mosquitoes. Follow-up treatments may be given every 12 months,Feb 18, 2024 · Heartgard: The Monthly Protector. Heartgard is a monthly oral medication that prevents heartworm disease, as well as treats and controls roundworms and hookworms. Key Benefits: Monthly dosing: Allows for flexibility and ease of discontinuation if necessary. Palatable chew: Dogs often see it as a treat, making administration easy. ProHeart ® 6, the same microsphere formulation as ProHeart 12 but administered at one-third the dose (0.17 mg/kg) of ProHeart 12, was 100% effective in preventing the development of a susceptible heartworm strain for …ProHeart 12 prevents the development of heartworm disease caused by D. immitis for 12 months. For dogs not previously on heartworm preventive or having lapsed beyond 12 months of a prior ProHeart 12 dose, the product should be given within 1 month of exposure to mosquitoes. Follow-up treatments may be given every 12 months,ProHeart 12 eliminates the larval and adult stages of A. caninum and U. stenocephala present at the time of treatment. Re-infection with A. caninum and U. stenocephala may occur sooner than 12 months. Dose: The recommended subcutaneous dose is 0.05(0.Proheart is an INJECTABLE heartworm prevention that is only given every 6 months! …” Racine Veterinary Hospital writes: “Proheart 6 is an injectable heartworm prevention. 1 injection lasts 6 months, which means you don’t have to worry about missing a dose…” Eastpoint Vet writes: “Proheart injections are going well this month …ProHeart 12 eliminates the larval and adult stages of A. caninum and U. stenocephala present at the time of treatment. Re-infection with A. caninum and U. stenocephala may … The constituted suspension is for subcutaneous injection at the rate of 0.05 mL/kg body weight to provide 0.17 mg moxidectin/kg. ProHeart 6 can be administered to dogs 6 months of age and older. For growing dogs, dose to the average weight during the 6 month effective period. Administration may be repeated at 6 months intervals. ProHeart 6 is indicated for use in dogs six months of age and older for the prevention of heartworm disease caused by Dirofilaria immitis for 6 months. ProHeart 6 is indicated for the treatment of existing larval and adult hookworm (Ancylostoma caninum and Uncinaria stenocephala) infections. DOSAGE AND ADMINISTRATIONProHeart 6 administered at 3 times the recommended dose did not adversely affect the reproductive performance of male or female dogs. ProHeart 6 administered up to 5 times the recommended dose in 7-8 month old puppies did not cause any systemic adverse effects.ProHeart 6 and ProHeart 12 See Prescribing Information for ProHeart 6 and ProHeart 12. Use ProHeart 6 in dogs 6 months of age or older and ProHeart 12 in dogs 12 months of age or older. Do not administer to dogs that are sick, debilitated, underweight, have a history of weight loss, or to those previously found to be hypersensitive to the drug.Background In a previous study, it was demonstrated that ProHeart® 6 (PH6) (moxidectin, Zoetis) provided only about 20% efficacy in a small six-dog study against a macrocyclic lactone –resistant Dirofilaria immitis isolate (Jd2009–2) when dogs were inoculated with infective third-stage larvae (L3) at the end of the dosing period (ie, 180 …ProHeart 12 prevents the development of heartworm disease caused by D. immitis for 12 months. For dogs not previously on heartworm preventive or having lapsed beyond 12 months of a prior ProHeart 12 dose, the product should be given within 1 month ofJul 9, 2018 ... ... proheart early or late up to 2 weeks after ... what I would do if your dog misses a dose, dose ... dosing day and dose again in 30 days or whatever ...ProHeart 12 Dosing Chart ProHeart 12 vs. Heartgard for Dogs 🐾 Category: Toxicity Published on: March 28, 2024 March 28, 2024 Author: Bestie Paws Like: 26 Comment: 0 Leave a Reply Cancel reply Your email …Since ProHeart 12 is new, there’s not much information about its specific side effects yet. But it uses moxidectin … the same active ingredient as ProHeart 6 … and in a higher dose. So let’s look at the history of that drug. ProHeart 6 Adverse Reactions It’s heartworm preventive product, ProHeart 6 should be given within one month of the last dose of the former medication. ProHeart 6 eliminates the larval and adult stages of A. caninum and U. stenocephala present at the time of treatment. However, persistent effectiveness has not been established for this indication. Re-infection with A. caninum and The determination of the correct ProHeart dosage is a meticulous process that veterinarians undertake with the utmost care, ensuring the safety and efficacy of the treatment. The dosage is primarily based on the dog's weight, with ProHeart being available in different strengths to cater to a wide range of sizes.PHT-00009. ProHeart® 6 (moxidectin) delivers 6 months of heartworm disease prevention for dogs with 1 shot. Learn more here.Dose. ProHeart 12 Dosing Chart. Heartworm disease is a serious and potentially fatal condition in dogs, caused by parasitic worms living in the heart and …One COVID-19 vaccine is already under review for possible emergency authorization in December; its competitors are close behind. Once we have a vaccine—or maybe several—it will be ...Learn how to mix and administer ProHeart 12, a long-acting injection for dogs against heartworm disease and other parasites. Find the dosing chart for different weight … ProHeart 6 should be given within one month of the last dose of the former medication. ProHeart 6 eliminates the larval and adult stages of A. caninum and U. stenocephala present at the time of treatment. However, persistent efectiveness has not been established for this indication. Re-infection with A. caninum and U. stenocephala may occur ProHeart 6 is a veterinary drug for dogs to prevent and treat heartworm and hookworm infections. It is a two-part sustained release product with 3.4 mg moxidectin per vial. The recommended dose is 0.05 mL per kg body weight, subcutaneously, every six months. The web page provides dosage chart, injection technique, risk minimization action plan, and contraindications.Heartgard: The Monthly Protector. Heartgard is a monthly oral medication that prevents heartworm disease, as well as treats and controls roundworms and hookworms. Key Benefits: Monthly dosing: Allows for flexibility and ease of discontinuation if necessary. Palatable chew: Dogs often see it as a treat, making administration easy.ProHeart 12 is an extended-release injectable formulation of moxidectin for dogs 12 months of age or older. It protects against heartworm disease and other parasites for 12 months with one dose.Feb 12, 2019 ... Your dog's risk of developing heartworm depends on when the dose was missed, how many doses were missed, the medication used and how common ... One disadvantage to the "split-dose" method, in addition to the expense, is the need for 2 months' exercise restriction. In 55 dogs with severe heartworm disease (HWD) and treated in this 3-dose manner, 96% had a good or very good outcome with >98% negative for antigenemia 90 days post-therapy. 19 Although symptomatic and even fatal PTE can ... ProHeart 12 is a medication that prevents heartworm disease in dogs 12 months of age and older. Your veterinarian gives it to your dog via an injection and it protects your dog from developing heartworm disease for 12 full months. ProHeart 12 also treats common hookworm infections your dog may have at the time of injection.Indications. ProHeart 12 is indicated for use in dogs 12 months of age and older for the prevention of heartworm disease caused by Dirofilaria immitis for 12 months. ProHeart 12 is indicated for the treatment of existing larval and adult hookworm (Ancylostoma caninum and Uncinaria stenocephala) infections.If it is suspected that any of the chew has been lost, redosing is recommended. Dosage Chart. Image. The dosing chart for Heartgard Plus, showing the ...Feb 18, 2024 · ProHeart offers convenience with less frequent dosing, while Simparica Trio appeals to those who prefer oral administration. Round 3: Safety and Side Effects Both medications have demonstrated safety in numerous studies, but as with all treatments, side effects can occur. A Dose of Relief: The Cytopoint Dosing Chart. Cytopoint’s dosing is based on weight, and it’s administered via a subcutaneous injection. Key Takeaways: Cytopoint is tailored to your dog’s weight. A combination of vials may be required for a single dose. Repeat treatments every 4-8 weeks, or as needed.The constituted suspension is for subcutaneous injection at the rate of 0.05 mL/kg body weight to provide 0.17 mg moxidectin/kg. ProHeart 6 can be administered to dogs 6 months of age and older. For growing dogs, dose to the average weight during the 6 month effective period. Administration may be repeated at 6 months intervals.Abstract. Background: The safety of ProHeart® 12 (PH 12; extended-release injectable suspension; 10% moxidectin in glyceryl tristearate microspheres) was evaluated in four studies using Beagle dogs and one study using ivermectin-sensitive Collies. The recommended dose is 0.5 mg/kg subcutaneously once yearly. Methods: Study 1: safety … heartworm preventive product, ProHeart 6 should be given within one month of the last dose of the former medication. ProHeart 6 eliminates the larval and adult stages of A. caninum and U. stenocephala present at the time of treatment. However, persistent effectiveness has not been established for this indication. Re-infection with A. caninum and Bone broth is a nutritious and delicious way to get your daily dose of minerals, vitamins, and collagen. It’s also incredibly easy to make at home, so you can enjoy it any time you...ProHeart 6 is an injectable medication that is used in dogs 6 months of age or older to prevent heartworm disease. Your veterinarian will administer ProHeart 6 as a single injection under your dog’s skin. Once the drug is given, it continuously prevents heartworm disease for 6 months. Using ProHeart 6 means that you don’t need to …ProHeart 6 administered at 3 times the recommended dose did not adversely affect the reproductive performance of male or female dogs. ProHeart 6 administered up to 5 times the recommended dose in 7-8 month old puppies did …A single dose of 7.5 mg/kg (3X the recommended dose) can result in pulmonary inflammation, edema, and death. Daily administration of these doses for 14 days caused renal damage in healthy dogs. Adverse reactions, primarily at the injection sites, were seen at the recommended dose in clinical trials (see ADVERSE REACTIONS).This site is intended for U.S. Animal Healthcare Professionals. The product information provided in this site is intended only for residents of the United States. The products discussed herein may not have marketing authorization or …ProHeart 6 is indicated for use in dogs six months of age and older for the prevention of heartworm disease caused by . Dirofilaria immitis. for 6 months. ProHeart 6 is indicated for the treatment of existing larval and adult hookworm (Ancylostoma caninum. and . Uncinaria stenocephala) infections. DOSAGE AND ADMINISTRATIONProHeart® 12 (PH 12) (Zoetis, Parsippany, NJ, USA) uses the same microsphere technology as PH 6 but with a higher final concentration of microspheres, providing 3× (0.5 mg/kg moxidectin) the dose rate of PH 6.ProHeart 12 prevents the development of heartworm disease caused by D. immitis for 12 months. For dogs not previously on heartworm preventive or having lapsed beyond 12 months of a prior ProHeart 12 dose, the product should be given within 1 month of exposure to mosquitoes. Follow-up treatments may be given every 12 months,ProHeart 12 is an extended-release injectable formulation of moxidectin for dogs 12 months of age or older. It protects against heartworm disease and other parasites for 12 months with one dose.ProHeart® 6 (moxidectin) delivers 6 months of heartworm disease prevention for dogs with 1 shot. Learn more here.Since ProHeart 12 is new, there’s not much information about its specific side effects yet. But it uses moxidectin … the same active ingredient as ProHeart 6 … and in a higher dose. So let’s look at the history of that drug. ProHeart 6 Adverse Reactions It’sApr 9, 2021 ... to the second monthly dose. Mild injection site reactions occurred in six ProHeart 12 -treated dogs and were observed from one to seven days ...ProHeart 12 prevents the development of heartworm disease caused by D. immitis for 12 months. For dogs not previously on heartworm preventive or having lapsed beyond 12 months of a prior ProHeart 12 dose, the product should be given within 1 month ofAt THS, we have the resources to treat heartworm in shelter dogs using the AHS-recommended 3-dose melarsomine protocol, which is considered the safest and most effective treatment in most cases. However, at the outreach clinics, where prevalence typically reaches double digits, this is rarely an option.ProHeart Dose: Weight (lbs) / 2.2 = Kg Kg x 0.05mL = Dose ProHeart 12 is 3x more concentrated than ProHeart 6 ProHeart 12 0.5 mg moxidectin/kg ProHeart 6 0.17 mg moxidectin/kg ProHeartDVM.com ProHeart® 12 (moxidectin) For Extended-Release ... ProHeart 6 administered up to 5 times the recommended dose in 7-8 month old puppies did not cause any systemic adverse effects. In well controlled clinical field studies, ProHeart 6 was used in conjunction with a variety of veterinary products including anthelmintics, antiparasitics, antibiotics, analgesics, steroids, non-steroidal anti ... 0.50 mg ProHeart 6/kg bodyweight (high-dose) Route of Administration: Subcutaneous injection in the dorsum of the neck. Test Duration: 327 days (treatment to necropsy). Study Design: All dogs were determined to be negative for D. immitis by antigen test and modified Knott’s test prior to study initiation.ProHeart 12 is a veterinary injectable suspension for dogs to prevent and treat heartworm and hookworm infections. Learn about the dosage, administration, indications, contraindications, and risk minimization action plan of ProHeart 12.Our Purpose. At Zoetis we understand that dogs aren’t just pets, they are members of the family. We encourage every dog owner to visit a veterinarian on a regular basis. Annual check-ups and preventive care are the best ways to make sure your dog (s) stay active and healthy. Antibiotics, parasite control, skin issues, pain management and ...This extended-release injectable contains moxidectin as its active ingredient, a robust parasiticide targeting heartworm larvae. This grants 12 months of solid protection against canine heartworms with just one dose of ProHeart 12, giving dog owners a reassuring sense of security that their pet is protected year-round.ProHeart 12 prevents the development of heartworm disease caused by D. immitis for 12 months. For dogs not previously on heartworm preventive or having lapsed beyond 12 months of a prior ProHeart 12 dose, the product should be given within 1 month of exposure to mosquitoes. Follow-up treatments may be given every 12 months,The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.Preventive efficacy of six monthly oral doses of Simparica Trio ®, Heartgard ® Plus, and Interceptor ® Plus against a macrocyclic lactone-resistant strain (ZoeLA) of …Extended Protection: ProHeart 6 provides six months of continuous heartworm disease prevention, while ProHeart 12 offers a full year of coverage. Convenience: A single injection eliminates the need for monthly reminders. Veterinarian-Administered: Ensures proper dosage and offers an opportunity for a health check-up.The lethal dose of diphenhydramine, the generic name of Benadryl, varies significantly from person to person because of differences in weight and metabolism.12 chances to miss a dose! When life gets busy, it can be tough to stay on top of monthly dosing— • and many pet owners do forget.2 Dogs may vomit or spit out the chews, which means you may have to redose. Some dogs refuse to eat "treat-like Is ProHeartApr 9, 2021 ... to the second monthly dose. Mild injection site reactions occurred in six ProHeart 12 -treated dogs and were observed from one to seven days ...ProHeart 12 prevents the development of heartworm disease caused by D. immitis for 12 months. For dogs not previously on heartworm preventive or having lapsed beyond 12 months of a prior ProHeart 12 dose, the product should be given within 1 month of exposure to mosquitoes. Follow-up treatments may be given every 12 months,ProHeart 12 is indicated for use in dogs 12 months of age and older for the accurate dosing calculate each dose based on the dog's weight at the time ... proheart pi ProHeart® 6(moxidectin) ProHeart 6 is indicated for use in dogs six months of age and older for the calculate each dose based on the dog's weight at the time of treatment. proheartcis piSep 6, 2019 · Over the past 11 years an estimated 12.4 million doses have been distributed there. More recently, PH 12 is also being marketed in a number of Asian and Latin American countries. In the USA, ProHeart ® 6 (PH 6) employs the same microsphere suspension as PH 12 at a lower dosage that protects against heartworm disease for 6 months. Shortly after ... ProHeart 6 administered up to 5 times the recommended dose in 7-8 month old puppies did not cause any systemic adverse effects. In well controlled clinical field studies, ProHeart 6 was used in conjunction with a variety of veterinary products including anthelmintics, antiparasitics, antibiotics, analgesics, steroids, non-steroidal anti ... Methods Study 1: safety margin was evaluated as 3 treatments of PH 12 (0× (control); 1× (recommended dose); 3× (3 times recommended dose) and 5× (5 times recommended dose) in 12 months via clinical observations, body weights, food consumption, injection site observations, physical examinations, moxidectin tissue assay, …Apr 9, 2021 ... to the second monthly dose. Mild injection site reactions occurred in six ProHeart 12 -treated dogs and were observed from one to seven days ...The lethal dose of diphenhydramine, the generic name of Benadryl, varies significantly from person to person because of differences in weight and metabolism.

Cytopoint has been shown to be effective for the treatment of dogs against allergic dermatitis and atopic dermatitis. References: 1. Data on file, Study No. C863R-US-12-018, 2014, Zoetis Inc. 2. Kanji N, Coe JB, Adams CL, et al. Effect of veterinarian-client-patient interactions on client adherence to dentistry and surgery recommendations in .... Fidium ont

This extended-release injectable contains moxidectin as its active ingredient, a robust parasiticide targeting heartworm larvae. This grants 12 months of solid protection against canine heartworms with just one dose of ProHeart 12, giving dog owners a reassuring sense of security that their pet is protected year-round.ProHeart 12 is a medication that prevents heartworm disease in dogs 12 months of age and older. Your veterinarian gives it to your dog via an injection and it protects your dog from developing heartworm disease for 12 full months. ProHeart 12 also treats common hookworm infections your dog may have at the time of injection.ProHeart 12 prevents the development of heartworm disease caused by D. immitis for 12 months. For dogs not previously on heartworm preventive or having lapsed beyond 12 months of a prior ProHeart 12 dose, the product should be given within 1 month of exposure to mosquitoes. Follow-up treatments may be given every 12 months, ProHeart 12 Prescribing Information. ProHeart® 6 (moxidectin) delivers 6 months of heartworm disease prevention for dogs with 1 shot. Learn more here. Medicine Matters Sharing successes, challenges and daily happenings in the Department of Medicine ARTICLE: Valganciclovir Dosing for Cytomegalovirus Prophylaxis in Solid-organ Tran...Medicine Matters Sharing successes, challenges and daily happenings in the Department of Medicine ARTICLE: Cycloserine did not increase depression incidence or severity at standard...PROHEART a monthly heartworm preventative tablet. HEARTGUARD a monthly heartworm prevention medication which is available as a 'chewable' treat or as a plain ...ProHeart 6 (Moxidectin) is the only FDA-approved heartworm shot, and it provides six months of protection. It also treats hookworm infections. ProHeart 6 is a unique preventative option because it uses microspheres to prolong the effects of the active ingredient moxidectin. Microspheres are small, solid spheres made of absorbable lipids.The animal health information contained herein is provided for educational purposes only and is not intended to replace discussions with an animal healthcare professional. All decisions regarding the care of a veterinary patient must be made with an animal healthcare professional, considering the unique characteristics of the patient.Jul 2, 2019 · The effectiveness of ProHeart® 12 for the treatment of existing larval and adult hookworms was established by referencing the data presented in the Freedom of Information Summaries for the original approval of ProHeart® 6 (moxidectin) dated June 6, 2001 (NADA 141-189), and the supplemental approval dated June 13, 2002. It’s available in four dosing sizes (2-8 lbs., 8.1-25 lbs., 25.1-50 lbs., and 50.1-100 lbs.). Dogs over 100 pounds can still take this medication but will require a combination of chewables for appropriate dosing. Dogs must be at least 2 pounds in size and 6 weeks or older to take this prevention. Simparica TrioMedicine Matters Sharing successes, challenges and daily happenings in the Department of Medicine ARTICLE: Cycloserine did not increase depression incidence or severity at standard...ZoetisProHeart 12 eliminates the larval and adult stages of A. caninum and U. stenocephala present at the time. of treatment. Re-infection with A. caninum and U. stenocephala may occur sooner than 12 months. Dose: The recommended subcutaneous dose is 0.05 mL of the constituted suspension/kg body weight. (0.023 mL/lb).heartworm preventive product, ProHeart 6 should be given within one month of the last dose of the former medication. ProHeart 6 eliminates the larval and adult stages of A. caninum and U. stenocephala present at the time of treatment. However, persistent effectiveness has not been established for this indication. Re-infection with A. caninum andProHeart 6 should be given within one month of the last dose of the former medication. ProHeart 6 eliminates the larval and adult stages of A. caninum and U. stenocephala present at the time of treatment. However, persistent efectiveness has not been.

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